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Published on: July 21, 2023
Systematic literature review and meta-analysis of cardiovascular risk factor management in selected Asian countries
Eric J Yeh1, Ruth Bartelli Grigolon2, Sarah Ramalho Rodrigues2
1Amgen Inc. Thousand Oaks, CA 91320, USA.
Insights
Management of hypertension, dyslipidemia, and diabetes mellitus is suboptimal across the Asia-Pacific region. Awareness, treatment, and control rates for these cardiovascular risk factors require significant improvement in APAC countries.
Area of Science:
- Cardiovascular Health
- Public Health
- Epidemiology
Background:
- Hypertension, dyslipidemia, and diabetes mellitus are significant cardiovascular risk factors.
- Understanding their management status in the Asia-Pacific region (APAC) is crucial for public health initiatives.
Purpose of the Study:
- To systematically review and meta-analyze the awareness, treatment, and control rates of hypertension, dyslipidemia/hypercholesterolemia, and diabetes mellitus in adults across 11 APAC countries/regions.
Main Methods:
- Systematic literature review and meta-analysis.
- Inclusion of 138 studies from 11 APAC countries/regions.
- Pooled analysis of awareness, treatment, and control rates for key cardiovascular risk factors.
Main Results:
- Dyslipidemia showed the lowest pooled rates among the studied risk factors.
- Awareness levels for diabetes mellitus, hypertension, and hypercholesterolemia were comparable.
- Hypercholesterolemia had lower treatment rates but higher control rates than hypertension.
Conclusions:
- The management of hypertension, dyslipidemia, and diabetes mellitus is suboptimal in the studied APAC countries.
- There is a critical need for improved strategies to enhance the management of these prevalent cardiovascular risk factors in the region.
Abstract:
Aim: There is a need to understand the management status of hypertension, dyslipidemia/hypercholesterolemia, and diabetes mellitus in the Asia-Pacific region (APAC). Methods: We conducted a systematic literature review and meta-analysis to summarize the awareness, treatment, and/or control rates of these risk factors in adults across 11 APAC countries/regions. Results: We included 138 studies. Individuals with dyslipidemia had the lowest pooled rates compared with those with other risk factors. Levels of awareness with diabetes mellitus, hypertension, and hypercholesterolemia were comparable. Individuals with hypercholesterolemia had a statistically lower pooled treatment rate but a higher pooled control rate than those with hypertension. Conclusion: The management of hypertension, dyslipidemia, and diabetes mellitus was suboptimal in these 11 countries/regions.
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