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Published on: March 29, 2018
Prevalence of molar incisor hypomineralization in India: A systematic review and meta-analysis
Ashveeta J Shetty1, Uma B Dixit1, Richard Kirubakaran2
1Department of Pediatric and Preventive Dentistry, D. Y. Patil University, School of Dentistry, Navi Mumbai, Maharashtra, India.
Research Question:
To estimate the pooled prevalence of molar incisor hypomineralization (MIH) in children from India.
Research Protocol:
The PRISMA guidelines were followed.
Literature Search:
An electronic search of the databases was performed to find prevalence studies of MIH in children above age 6 years in India.
Data Extraction:
Two authors independently extracted the data from the 16 included studies.
Quality Appraisal:
The risk of bias was assessed using a modified version of the Newcastle-Ottawa Scale adapted for cross-sectional studies.
Data Analysis:
The pooled prevalence estimate of MIH was calculated using logit transformed data with inverse variance approach in a random-effects model with 95% confidence interval (CI). Heterogeneity was assessed with the I2 statistic. The subgroups were analyzed to assess the pooled prevalence of MIH according to sex, arch-wise proportion of MIH-affected teeth, and proportion of children with the MIH phenotypes.
Results And Interpretation Of Results:
Sixteen studies included in the meta-analysis represented 7 states of India. A total of 25,273 children were included in the meta-analysis. The pooled prevalence of MIH in India was estimated to be 10.0% (95% CI: 0.07, 0.12) with significantly high heterogeneity between the included studies. The pooled prevalence did not vary according to sex. The pooled proportions of MIH-affected teeth were similar in the maxillary and mandibular arches. The pooled proportion of children with MH phenotype was higher (56%) than those with M + IH phenotype (44%). Further studies with standardized criteria for recording MIH are needed to ascertain the prevalence of MIH in India.
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