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Updated: Aug 8, 2025

Ultrasonographic Evaluation of Breast Cancer-related Lymphedema
Published on: January 12, 2017
Case report and literature review on a large MBC with ulceration
1Traditional Chinese Medicine Department of Wuhan No.1 Hospital, China.
Rationale:
Metaplastic breast cancer (MBC) is a rare tumor of the breast, and skin ulceration of breast tumors is a difficult clinical problem that reduces the patient's quality of life.
Patient Concerns:
There are currently no Standard Treatment Guidelines for MBC at present, and the treatment for the skin ulceration of breast tumors is limited in clinics.
Diagnosis:
Here, we report the case of a patient with a large MBC and skin ulceration, accompanied by exudation and odor.
Intervention:
The combined treatment of albumin paclitaxel and carrelizumab (anti-PD-1 immunotherapy) was effective in reducing the tumor, but it increased the severity of the skin ulceration. After taking traditional Chinese medicine, the skin ulceration healed completely. Then the patient underwent a mastectomy and radiotherapy.
Outcomes:
The patient has a high quality of life and was in good condition after the comprehensive treatment.
Lessons:
This suggests that traditional Chinese medicine may have a good auxiliary therapeutic effect on the skin ulceration of MBC.
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