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Product-driven high-throughput screening of industrial filamentous actinomycetes
Yue Zhang1, Xuemei Zhang2, Meng Wang1
1Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Trends in Biotechnology
|March 2, 2023
Abstract:
Traditional strain breeding of industrial filamentous actinomycetes has long been hampered by insufficient screening throughput. From microtiter plate based methods to droplet-based microfluidic screening, various novel product-driven high-throughput screening (HTS) methods have pushed the screening speed limit towards a minimum of hundreds of strains per second with single cell resolution.

