Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioequivalence: Overview01:16

Bioequivalence: Overview

1.1K
Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...
1.1K
Factors Affecting Drug Distribution: Physiological Barriers01:23

Factors Affecting Drug Distribution: Physiological Barriers

271
Drug distribution in the body is intricately regulated by various physiological barriers that control the passage of substances. These include the capillary endothelial barrier, the blood-brain, blood-cerebrospinal fluid, blood-placental, and blood-testis barriers.
The capillary endothelial barrier allows only smaller molecules below 600 Da (Daltons) to pass through. It also restricts drugs like heparin that are bound to blood components, limiting their movement within the bloodstream.
The...
271
Drug Distribution: Overview01:11

Drug Distribution: Overview

248
Drug distribution within the body is a dynamic process involving the movement of a drug in two directions across various compartments: from the bloodstream into tissues (tissue uptake) and from tissues back into the bloodstream (tissue release or redistribution). This process is passive and primarily driven by two variables: the concentration gradient between the bloodstream and the extravascular tissues and the drug's ability to cross the cell membrane.
Initially, the free drug in the...
248
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

3.7K
A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
3.7K
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

426
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
426
Factors Affecting Drug Distribution: Miscellaneous Factors01:19

Factors Affecting Drug Distribution: Miscellaneous Factors

435
Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
435

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physical rehabilitation techniques for spinal cord injury: A scoping review.

African journal of disability·2026
Same author

The assessment and treatment of kratom dependence: findings from a physician survey in Malaysia.

The American journal of drug and alcohol abuse·2026
Same author

Universal progression of structure and dynamics in colloidal nanocrystal gels during salt-accelerated aging.

Science advances·2026
Same author

Comprehensive blood pressure management to improve early postpartum blood pressure parameters: A randomized controlled trial.

Pregnancy (Hoboken, N.J.)·2026
Same author

Kratom use in adolescents and college students: a systematic review of prevalence, patterns, and risk factors across community and rehabilitation settings.

The American journal of drug and alcohol abuse·2026
Same author

A network analysis of depression, anxiety, and their associations with kratom (<i>Mitragyna speciosa</i>) use among people who previously used methamphetamine.

Journal of psychoactive drugs·2025

Related Experiment Video

Updated: Aug 8, 2025

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.6K

Deconstructing Differential Drug Coverage within a Malaysian Media Source.

O Hayden Griffin1, Lindsay Leban1, Darshan Singh2

  • 1Department of Criminal Justice, University of Alabama at Birmingham, Birmingham, AL, USA.

Journal of Psychoactive Drugs
|March 2, 2023
PubMed
Summary
This summary is machine-generated.

Media coverage of five drugs in Malaysia shows similarities and differences. While all drugs were framed within a criminal justice context, specific drug types were associated with varying themes, crimes, and locations, indicating differential threat perception.

Keywords:
Drugsmedia coveragemoral panic

More Related Videos

Diagonal Method to Measure Synergy Among Any Number of Drugs
12:08

Diagonal Method to Measure Synergy Among Any Number of Drugs

Published on: June 21, 2018

18.7K
Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
08:54

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

7.8K

Related Experiment Videos

Last Updated: Aug 8, 2025

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
19:57

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

18.6K
Diagonal Method to Measure Synergy Among Any Number of Drugs
12:08

Diagonal Method to Measure Synergy Among Any Number of Drugs

Published on: June 21, 2018

18.7K
Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples
08:54

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

7.8K

Area of Science:

  • Social Sciences
  • Media Studies
  • Criminology

Background:

  • Media reporting on drugs often lacks accuracy and sensationalizes content.
  • There's a tendency to generalize drug harm and overlook distinctions between drug types.

Purpose of the Study:

  • To analyze and compare media coverage of specific drugs in Malaysia.
  • To deconstruct thematic differences in reporting based on drug type.

Main Methods:

  • A content analysis of 487 news articles over two years from a Malaysian national media outlet.
  • Articles were coded for themes, associated crimes, and locations concerning five drugs: amphetamines, opiates, cannabis, cocaine, and kratom.

Main Results:

  • All five drugs were predominantly framed within a criminal justice context, emphasizing concerns about spread and abuse.
  • Coverage varied significantly, with differences noted in associations with violent crime, regional focus, and discussions of legality.
  • Certain drugs were portrayed as greater threats, reflecting societal and political influences on drug policy debates.

Conclusions:

  • Media coverage of drugs in Malaysia exhibits both uniform framing (criminal justice) and drug-specific variations.
  • These variations highlight differential threat perceptions and the influence of socio-political factors on drug discourse and policy.
  • Understanding these nuances is crucial for accurate public perception and informed drug policy discussions.