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Related Concept Videos

Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

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Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
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Related Experiment Video

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A Novel Murine Model of Arteriovenous Fistula Failure: The Surgical Procedure in Detail
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A deep learning algorithm to quantify AVF stenosis and predict 6-month primary patency: a pilot study.

Jae Hyon Park1, Jongjin Yoon1, Insun Park2

  • 1Department of Radiology, Yonsei University College of Medicine, Seoul, Republic of Korea.

Clinical Kidney Journal
|March 3, 2023
PubMed
Summary
This summary is machine-generated.

A novel deep convolutional neural network (DCNN) model effectively predicts arteriovenous fistula (AVF) stenosis and 6-month patency using shunt sounds. This AI approach surpasses traditional machine learning models for improved AVF management.

Keywords:
angioplastyarteriovenous fistulaauscultationconvolutional neural networkprimary patency

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Area of Science:

  • Medical Imaging and Artificial Intelligence
  • Cardiovascular Surgery
  • Nephrology

Background:

  • Arteriovenous fistula (AVF) dysfunction is a common complication in hemodialysis patients.
  • Accurate prediction of AVF stenosis and primary patency (PP) is crucial for effective patient management.
  • Current methods for assessing AVF status can be invasive or lack precision.

Purpose of the Study:

  • To develop and evaluate a deep convolutional neural network (DCNN) model for predicting AVF stenosis and 6-month primary patency (PP).
  • To assess the model's performance using AVF shunt sounds converted to melspectrograms.
  • To compare the DCNN model's diagnostic performance against various machine learning (ML) models utilizing clinical data.

Main Methods:

  • Prospective recruitment of 40 dysfunctional AVF patients.
  • Recording AVF shunt sounds pre- and post-percutaneous transluminal angioplasty using a wireless stethoscope.
  • Converting audio recordings to melspectrograms for analysis by a ResNet50-based DCNN model.
  • Comparing the DCNN model with logistic regression, decision tree, and support vector machine models trained on clinical data.

Main Results:

  • Melspectrograms qualitatively correlated with AVF stenosis severity, showing higher amplitude at mid-to-high frequencies during systole for more severe stenosis.
  • The melspectrogram-based DCNN model accurately predicted the degree of AVF stenosis.
  • The DCNN model achieved a superior area under the receiver operating characteristic curve (≥0.870) for predicting 6-month PP compared to ML models using clinical data (LR: 0.783, DT: 0.766, SVM: 0.733) and a spiral-matrix DCNN model (0.828).

Conclusions:

  • The developed melspectrogram-based DCNN model demonstrates high accuracy in predicting AVF stenosis.
  • This AI-driven approach significantly outperforms traditional ML models based on clinical data for predicting 6-month AVF primary patency.
  • The findings suggest a promising non-invasive method for monitoring AVF health and improving patient outcomes.