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Why Studying Urgency Is Urgent.

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Bowel urgency is a common and debilitating ulcerative colitis symptom impacting quality of life. Addressing this symptom requires multidisciplinary care and inclusion in clinical assessments.

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Area of Science:

  • Gastroenterology
  • Inflammatory Bowel Disease Research

Background:

  • Bowel urgency is a prevalent and severely impactful symptom in ulcerative colitis (UC).
  • It significantly impairs patients' daily lives, affecting education, employment, and social engagement.
  • Urgency occurs during both active disease flares and remission, indicating complex underlying mechanisms.

Purpose of the Study:

  • To outline the prevalence and impact of bowel urgency in ulcerative colitis patients.
  • To describe the postulated pathophysiologic mechanisms driving bowel urgency.
  • To recommend the integration of urgency assessment into clinical care and research.

Main Methods:

  • Literature review on bowel urgency in ulcerative colitis.
  • Analysis of postulated pathophysiologic mechanisms.
  • Discussion of clinical assessment and management strategies.

Main Results:

  • Bowel urgency is a pivotal symptom affecting patient quality of life in UC.
  • Mechanisms involve acute inflammation and chronic inflammation sequelae.
  • Urgency is underrepresented in clinical indices and trial endpoints.

Conclusions:

  • Explicitly inquiring about and managing bowel urgency is crucial for UC patients.
  • A multidisciplinary approach involving gastroenterologists, psychological support, and continence services is recommended.
  • Incorporating urgency into clinical care and research can improve patient-reported outcomes and treatment satisfaction.