A rare case of Klippel-Trenaunay syndrome presenting with chronic myeloid leukemia
Çağrı Coşkun1, Tekin Aksu1, Fatma Gümrük1
1Department of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.
Background:
Klippel-Trenaunay syndrome (KTS) is an overgrowth syndrome associated with capillary/venous/ lymphatic malformations with limb hypertrophy and cancer risk. Various cancers, mostly Wilms tumor, have been reported in patients with KTS, but not leukemia. Chronic myeloid leukemia (CML) is also a rare disease in children, where there is no known disease or syndrome to predispose to CML.
Case:
We report a case of CML incidentally diagnosed in a child with KTS when he was bleeding from surgery of the left groin for vascular malformation.
Conclusions:
This case reflects the variety of cancer types that may accompany KTS and provides information about CML prognosis in such patients.
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