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Impact of Multidisciplinary Collaborative Intervention on Isolation Implementation in Prevention and Control of

Ying Wang1, Xin-Ping Zhang2, Xiao-Quan Lai3

  • 1Naning Drum Tower Hospital Affiated to Nanjing University Medical School, Nanjing, 210008, China.

Current Medical Science
|March 3, 2023
PubMed
Abstract

Insights

Multidisciplinary interventions significantly improved isolation order compliance for multidrug-resistant organisms (MDROs). This enhances hospital infection control and management of resistant bacteria.

Area of Science:

  • Infectious Diseases
  • Hospital Epidemiology
  • Public Health

Background:

  • Contact precautions, including isolation, are crucial for controlling multidrug-resistant organisms (MDROs).
  • Clinical implementation of isolation measures for MDROs is often suboptimal.
  • Effective strategies are needed to improve adherence to isolation protocols in healthcare settings.

Purpose of the Study:

  • To evaluate the impact of a multidisciplinary collaborative intervention on the implementation of isolation for patients with MDROs.
  • To identify factors influencing the adherence to isolation measures in clinical practice.

Main Methods:

  • A multidisciplinary intervention was implemented in a tertiary hospital.
  • Retrospective analysis of isolation orders for 1338 patients with MDROs before and after the intervention.
  • Statistical analysis, including univariate and multivariate logistic regression, was used to identify influencing factors.

Main Results:

  • The overall isolation order issuance rate increased from 33.12% to 75.88% post-intervention (P<0.001).
  • The multidisciplinary intervention was a significant promoting factor for isolation order issuance (P<0.001, OR=0.166).
  • Length of stay, department, and microorganism type also influenced isolation implementation.

Conclusions:

  • Despite improvements, isolation implementation rates remain below desired standards.
  • Multidisciplinary collaborative interventions effectively enhance physician compliance with isolation measures.
  • These findings offer valuable insights for improving hospital infection management and controlling MDROs.
Keywords:
isolation implementation rateissuance of isolation ordersmultidisciplinary collaborative interventionmultidrug-resistant organism infection and colonization

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