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Updated: Aug 8, 2025
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Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
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Optical coherence tomography angiography parameters after cataract surgery.
Ramin Nourinia1,2, Ali Kiani1,2, Kiana Hassanpour1,2
1Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Paidarfard St., Boostan 9 St., Pasdaran, Tehran, 16666, Iran.
International Ophthalmology
|March 3, 2023
Summary
Cataract surgery increases macular vessel density and central macular thickness while reducing the foveal avascular zone (FAZ). Postoperative inflammation may explain these changes in blood flow.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Vascular Biology
Background:
- Cataract surgery is a common procedure.
- Understanding its impact on macular vasculature is crucial for patient outcomes.
Purpose of the Study:
- To evaluate changes in macular blood flow after cataract surgery using optical coherence tomography angiography (OCT-A).
Main Methods:
- Prospective case series of 50 patients undergoing cataract surgery.
- OCT-A imaging and ocular examinations at baseline, 1, and 3 months postoperatively.
- Assessed foveal avascular zone (FAZ) area, vessel density (VD) of superficial and deep plexuses, and central macular thickness (CMT).
Main Results:
- Significant reduction in FAZ area post-surgery (P < 0.001).
- Significant increase in macular VD in both superficial and deep plexuses.
- Significant increase in CMT post-surgery, correlating positively with cataract grade.
Conclusions:
- Uncomplicated cataract surgery leads to increased macular CMT and VD, with reduced FAZ area.
- Postoperative inflammation is a potential factor influencing these vascular changes.
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