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Myxoid Liposarcoma: How to Stage and Follow
1Division of Medical Oncology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. Ho.thanh@mayo.edu.
Current Treatment Options in Oncology
|March 3, 2023
Summary
Whole-body MRI is recommended for staging new myxoid liposarcoma (MLPS) diagnoses, as it can detect extrapulmonary disease missed by PET and CT scans. Surveillance imaging should be personalized based on tumor size and characteristics.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Myxoid liposarcoma (MLPS) is a rare soft tissue sarcoma.
- MLPS has a tendency to metastasize to soft tissue and bone.
Purpose of the Study:
- To review imaging modalities for myxoid liposarcoma (MLPS).
- To discuss recent findings on survival and prognostic tools in MLPS.
Main Methods:
- Literature review of studies evaluating imaging in MLPS.
- Analysis of recent publications on MLPS survival and prognostic factors.
Main Results:
- Whole-body MRI is a valuable tool for staging MLPS, potentially identifying extrapulmonary metastases missed by PET and CT.
- Tailored surveillance imaging is suggested, with increased frequency and duration for larger tumors or those with a round cell component.
Conclusions:
- Whole-body MRI should be considered in the initial staging of MLPS.
- Personalized surveillance strategies are crucial for effective MLPS monitoring.
