Related Experiment Video
Updated: Jul 20, 2026

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
Trends in Traumatic Brain Injury Among U.S. Service Members Deployed in Iraq and Afghanistan, 2002-2016
Tuan D Le1, Jennifer M Gurney2, Karan P Singh3
1U.S. Army Institute of Surgical Research, Fort Sam Houston, Texas; Department of Epidemiology and Biostatistics, UT Tyler School of Medicine, The University of Texas at Tyler Health Science Center, Tyler, Texas.
Traumatic brain injury (TBI) affects one-third of injured service members. Findings indicate a need for enhanced preventive measures and field management guidelines to reduce TBI frequency and severity in military personnel.
Area of Science:
- Military medicine
- Neuroscience
- Epidemiology
Background:
- Traumatic brain injury (TBI) is a significant health concern for deployed service members, with limited understanding of its risk factors and trends.
- Recent conflicts have seen an increase in TBI cases among military personnel.
Purpose of the Study:
- To characterize the epidemiology of TBI in U.S. service members.
- To analyze the impact of policy, care, equipment, and tactics on TBI over a 15-year period.
Main Methods:
- Retrospective analysis of U.S. Department of Defense Trauma Registry data from 2002-2016.
- Inclusion of service members treated for TBI at Role 3 medical facilities in Iraq and Afghanistan.
- Utilized Joinpoint and logistic regression for examining risk factors and trends.
Main Results:
- Nearly one-third (32.4%) of injured service members at Role 3 facilities sustained TBI, predominantly mild (75.8%).
- TBI rates were higher in males, in Afghanistan compared to Iraq, and in combat versus non-combat scenarios.
- TBI proportion increased over time, particularly mild and moderate TBI, with a notable rise between 2005 and 2011.
Conclusions:
- One-third of injured service members experienced TBI, highlighting the need for improved prevention strategies.
- Implementing clinical guidelines for mild TBI field management could alleviate healthcare system burdens.
- Enhanced capabilities for military field hospitals may be necessary to address TBI cases effectively.
More Related Videos
09:49Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
04:02Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
Published on: November 29, 2024