Related Experiment Video

Updated: Aug 8, 2025

Validated Immunochemical Assay for Comprehensive Determination of the Human Epidermal Growth Factor Receptor 2 Released from and Bound to Cells
08:28

Validated Immunochemical Assay for Comprehensive Determination of the Human Epidermal Growth Factor Receptor 2 Released from and Bound to Cells

Published on: May 9, 2025

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[Targeting HER2 in colorectal cancer]

Eléonore Spitzer1, Pascale Cervera2, Thierry André1

  • 1Saint-Antoine Hospital, AP-HP, SIRIC CURAMUS, Inserm, unité mixte de recherche scientifique 938, centre de recherche Saint-Antoine, équipe instabilité des microsatellites et cancer, équipe labellisée par la Ligue nationale contre le cancer, Department of Medical Oncology, Paris Sorbonne University, 184, rue du faubourg Saint-Antoine, 75012 Paris, France.

Bulletin Du Cancer
|March 4, 2023
PubMed
Summary

Human Epidermal Growth Factor Receptor 2 (HER2) overexpression occurs in 2-5% of metastatic colorectal cancer (mCRC) and is linked to poor prognosis. Investigating HER2-targeted therapies shows promising response rates in early trials.

Keywords:
Cancer colorectalColorectal cancerHER2Targeted therapyThérapie cibléeTrastuzumab

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