Related Experiment Video
Updated: Aug 8, 2025
08:12
Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
19.2K
[Machine perfusion in kidney transplantation].
Fruzsina Tóth1, Attila Szijártó2, László Piros2
11 Semmelweis Egyetem, Általános Orvostudományi Kar, Elméleti és Transzlációs Orvostudományok Doktori Iskola Budapest, Üllői út 78., 1082 Magyarország.
Orvosi Hetilap
|March 5, 2023
Summary
Machine perfusion improves kidney graft survival, especially for extended criteria donation. This technique offers organ preservation and conditioning, with ongoing research into therapeutic applications to reduce injury and immunogenicity.
Area of Science:
- Nephrology
- Transplantation Surgery
- Medical Engineering
Background:
- Organ transplantation faces a critical shortage, with a growing patient waiting list.
- Extended criteria donation and improved organ preservation are key strategies to address this shortage.
- Machine perfusion has demonstrated efficacy in reducing delayed graft function and enhancing graft survival.
Conclusions:
- Machine perfusion is a vital tool in modern kidney transplantation, particularly for extended criteria organs.
- Ongoing research into therapeutic applications during perfusion may further optimize graft outcomes.
- Machine perfusion offers both preservation and conditioning benefits, advancing transplantation possibilities.
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