Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

440
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
440
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.7K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.7K
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
Methods of Documentation VI: Case Management Model01:15

Methods of Documentation VI: Case Management Model

612
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
612

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of Item Banks to Assess Financial Hardship in Cancer Survivors Using Item Response Theory.

Frontiers in cancer control and society·2026
Same author

Administrative Burden as a Potential Cause of Financial Hardship and Poor Mental Health in Cancer: A Mixed Methods Study.

JCO oncology practice·2026
Same author

Serious Illness and Health Care Threats to Personal Legacy Goals.

The Permanente journal·2026
Same author

How and Under What Conditions Do Patient Portals Improve Cancer Screening Completion: A Scoping Review.

AJPM focus·2026
Same author

Opportunities and Challenges for Addressing Financial Hardship as an Integrated Part of Cancer Care Delivery.

Journal of the National Cancer Institute·2026
Same author

Uptake and timing of risk-reducing gynecologic surgery among individuals with Lynch syndrome identified via population screening.

Familial cancer·2026

Related Experiment Video

Updated: Aug 8, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.2K

Human-Centered Design Study to Inform Traceback Cascade Genetic Testing Programs at Three Integrated Health Systems.

Katrina M Romagnoli1, Alanna Kulchak Rahm2, Mary Cabell Jonas3

  • 1Department of Health System Sciences, Geisinger Health System, Danville, Pennsylvania, USA.

Public Health Genomics
|March 5, 2023
PubMed
Summary

Traceback genetic testing for ovarian cancer is valuable. Patients prefer discussing results with a knowledgeable clinician, with directed communication being ideal for invitations and reminders.

Keywords:
Cascade testingGenetic testingHuman-centered designOvarian cancerTraceback

More Related Videos

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
10:42

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

3.0K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

13.7K

Related Experiment Videos

Last Updated: Aug 8, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.2K
Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics
10:42

Design to Implementation Study for Development and Patient Validation of Paper-Based Toehold Switch Diagnostics

Published on: June 17, 2022

3.0K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

13.7K

Area of Science:

  • Oncology
  • Genetics
  • Public Health

Background:

  • Traceback genetic testing can identify hereditary breast and ovarian cancer (HBOC) syndrome in individuals and their relatives.
  • Successful implementation requires understanding patient experiences, barriers, and preferences.

Purpose of the Study:

  • To explore patient preferences for ovarian cancer genetic testing communication and experiences.
  • To inform the design of human-centered traceback genetic testing programs.

Main Methods:

  • Remote, human-centered design research study.
  • Interviews with 70 participants (ovarian cancer probands and relatives with family history).
  • Rapid thematic analysis of interview data.

Main Results:

  • Five preferred experiences for traceback programs were identified.
  • Participants prefer discussing genetic testing with a knowledgeable clinician.
  • Directed communication for invitations was preferred over passive communication; repeated contact for reminders was acceptable.

Conclusions:

  • Participants recognize the value of traceback genetic testing and prefer clinician-led discussions.
  • Findings are informing the development of traceback cascade genetic testing programs.