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Related Concept Videos

Clinical Trials01:16

Clinical Trials

6.9K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
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Clinical Trials: Overview01:11

Clinical Trials: Overview

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Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Community Based Intervention01:30

Community Based Intervention

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Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
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Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

153
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
153
Blinding01:11

Blinding

2.5K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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Nurses' Legal Responsibilities I01:27

Nurses' Legal Responsibilities I

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In healthcare, informed consent is a crucial process that involves thoroughly communicating medical treatment options to patients, including benefits, risks, potential side effects, and alternatives. This process enables patients to make well-informed decisions about their care, ensuring they understand the implications of their choices before consenting to or refusing treatment.
The legal responsibilities of a nurse regarding informed consent include the following:
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Updated: Aug 8, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
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Community Informed Recruitment: A Promising Method to Enhance Clinical Trial Participation.

Shena Gazaway1, Marie Bakitas2, Felicia Underwood3

  • 1School of Nursing, University of Alabama at Birmingham (S.G., M.B.,), Birmingham, AL, USA; Center for Palliative and Supportive Care, University of Alabama at Birmingham (S.G., M.B., F.U., C.E., M.D., S.M., V.H., R.E.), Birmingham, AL, USA.

Journal of Pain and Symptom Management
|March 5, 2023
PubMed
Summary
This summary is machine-generated.

Community engagement significantly boosted palliative care clinical trial recruitment for under-represented groups. A novel strategy using community advisory groups (CAGs) and videos improved patient consent rates.

Keywords:
Community-enhanced recruitment methodsblack participantsrandomized control trial participant recruitmentrural participants

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Area of Science:

  • Palliative Care
  • Clinical Trial Recruitment
  • Health Disparities

Background:

  • Low recruitment in palliative care trials among Black and rural populations is linked to trust issues and barriers.
  • Community engagement strategies have shown success in increasing trial participation among under-represented groups.

Purpose of the Study:

  • To describe a successful community-engaged recruitment strategy in a multi-site randomized clinical trial (RCT).
  • To address low recruitment rates in palliative care clinical trials among Black and rural individuals.

Main Methods:

  • Utilized community-based participatory research principles and input from a Community Advisory Group (CAG).
  • Developed a novel recruitment strategy for the Community Tele-Pal RCT, involving CAG members in patient introductions.
  • Adapted strategy during pandemic restrictions by creating CAG member introduction videos.

Main Results:

  • Of 228 eligible patients, consent rates were similar between White (44.1%) and Black (46.6%) participants.
  • CAG-involved recruitment methods showed higher consent rates: coordinator/CAG video (58.8%) versus coordinator only (12.7%).

Conclusions:

  • A novel community-enhanced recruitment strategy can increase clinical trial participation.
  • This approach shows potential for engaging historically under-represented populations in palliative care research.