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Association between pediatric TBI and mental health and substance use disorders: A scoping review

Nasrin Adams Nejatbakhsh1,2, Danielle Dawson1, Mark Hutchison3

  • 1Addiction Medicine, Centre for Addiction and Mental Health, Toronto, Canada.

Brain Injury
|March 5, 2023
PubMed

Insights

Pediatric Traumatic Brain Injury (TBI) is linked to later mental health and substance use issues, but evidence is mixed. More research is needed to understand these connections and identify influencing factors.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Public Health

Background:

  • The long-term mental health and substance use disorder risks following pediatric Traumatic Brain Injury (TBI) are poorly understood.
  • This knowledge gap hinders the development of effective prevention and management strategies for affected children and adolescents.

Purpose of the Study:

  • To conduct a scoping review of existing literature on the relationship between pediatric TBI and subsequent mental health disorders and substance use.
  • To identify gaps in current research to guide future investigations.

Main Methods:

  • A comprehensive search of multiple databases was performed for original articles published between September 2002 and September 2022.
  • Screening of identified articles was conducted by two independent reviewers using established scoping review frameworks (Arksey and O'Malley, Levac et al.).

Main Results:

  • Six studies met the inclusion criteria for this scoping review.
  • The included studies comprised cross-sectional and prospective longitudinal cohort designs.

Conclusions:

  • A potential correlation exists between pediatric TBI and the development of certain mental health disorders and substance use.
  • Current evidence is often mixed and lacks control for confounding variables, highlighting the need for further rigorous research.
Abstract

Keywords:
Childaddictionanxietyconcussiondepressionmental health disorderpediatricsubstance usetraumatic brain injuryyouth

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