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Cyclohexenones via Michael Addition and Aldol Condensation: The Robinson Annulation01:27

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Robinson annulation is a base-catalyzed reaction for the synthesis of 2-cyclohexenone derivatives from 1,3-dicarbonyl donors (such as cyclic diketones, β-ketoesters, or β-diketones) and α,β-unsaturated carbonyl acceptors. Named after Sir Robert Robinson, who discovered it, this reaction yields a six-membered ring with three new C–C bonds (two σ bonds and one π bond).
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Reply to Robinson et al

Annika N Flynn1, Peter J Rogers1, Kevin D Hall2

  • 1Nutrition and Behaviour Unit, School of Psychological Science, University of Bristol, Bristol, UK.

The American Journal of Clinical Nutrition
|March 5, 2023
PubMed
Summary

No abstract available in PubMed .

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