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Updated: Aug 8, 2025
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Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
Published on: December 22, 2017
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Interrupted inferior vena cava with deep vein thrombosis
BJR Case Reports
|March 6, 2023
Summary
A rare interrupted inferior vena cava (IVC) with azygos continuation was diagnosed in a young man with flank pain. This vascular malformation was linked to deep vein thrombosis and Factor V Leiden, highlighting diagnostic considerations.
Area of Science:
- Vascular Malformations
- Embryology
- Radiology
Background:
- Interrupted inferior vena cava (IVC) with azygos continuation is a rare congenital anomaly.
- It is often asymptomatic but can be associated with deep vein thrombosis (DVT).
- Accurate diagnosis is crucial to avoid misinterpretation as other pathologies.
Observation:
- A 22-year-old male presented with flank and testicular pain, lower abdominal pain, and urinary symptoms.
- Contrast-enhanced CT revealed an interrupted IVC with azygos and hemiazygos vein dilation, bilateral iliac vein thrombosis, and left testicular vein thrombus.
- Findings suggested testicular vein thrombophlebitis.
Findings:
- The patient was diagnosed with interrupted IVC with azygos continuation and bilateral iliac vein thrombosis.
- Testicular vein thrombosis and thrombophlebitis were also identified.
- Hypercoagulability work-up revealed heterozygosity for Factor V Leiden mutation.
Implications:
- This case underscores the importance of recognizing interrupted IVC with azygos continuation in patients with venous thrombosis.
- Testicular vein thrombosis should be considered in the differential diagnosis of testicular pain, especially in the presence of prothrombotic disorders.
- Radiologists must be aware of this rare vascular anomaly to ensure correct diagnosis and management.
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