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Related Experiment Video

Updated: Aug 8, 2025

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Primary breast angiosarcoma: A case report.

Yu He1, Liyuan Qian2, Lang Chen3

  • 1Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.

Frontiers in Surgery
|March 6, 2023
PubMed
Summary
This summary is machine-generated.

Primary breast angiosarcoma (PBA) is a rare cancer. Tumor vascular embolization may reduce surgical risks for hemorrhage in PBA patients, though further research is needed.

Keywords:
DSA (digital subtraction angiography)breast angiosarcomacase reportchemotherapyradiotherapysurgery

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Area of Science:

  • Oncology
  • Vascular Biology

Background:

  • Primary breast angiosarcoma (PBA) is a rare malignancy (0.04% of breast cancers) with challenging diagnosis and poor prognosis.
  • Mastectomy is the standard treatment, but the efficacy of adjuvant therapies like chemotherapy or radiotherapy remains uncertain due to limited studies.

Observation:

  • A 17-year-old female presented with a rapidly growing, hemorrhaging right breast mass.
  • Needle biopsy confirmed angiosarcoma, but the tumor exhibited significant bleeding during procedures.
  • Angiography and tumor vascular embolization were performed due to the high bleeding risk.

Findings:

  • Tumor vascular embolization effectively reduced the risk of hemorrhage during surgery for primary breast angiosarcoma.
  • The patient underwent mastectomy followed by adjuvant chemotherapy.

Implications:

  • Tumor vascular embolization is a potentially valuable intervention for managing hemorrhage risk in primary breast angiosarcoma.
  • Further clinical studies are required to establish the definitive role and optimal strategies for adjuvant treatments in PBA.