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Updated: Aug 8, 2025

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Case report: A case of rectal metastatic squamous cell carcinoma from the esophagus
Junni Chen1, Shuai Zhang1, Jiawei Chen1
1Department of Radiation Oncology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Abstract:
Esophageal cancer is prone to distant metastasis, and the prognosis is very poor; the occurrence of intestinal metastasis is extremely rare, with atypical clinical manifestations. We report a case of rectal metastasis after surgery for esophageal squamous cell carcinoma. The patient was a 63-year-old male who was admitted to the hospital due to progressive dysphagia. He was diagnosed with moderately differentiated esophageal squamous cell carcinoma after the surgery. He was not treated with chemoradiotherapy after surgery and had recurrent blood in his stool at 9 months post-surgery; rectal metastasis of esophageal squamous carcinoma was diagnosed based on postoperative pathology. Because the patient had a positive rectal margin, we used adjuvant chemoradiotherapy and carrelizumab immunotherapy, achieving very good short-term efficacy. The patient is currently in a state of tumor-free survival and is still being closely followed up and treated. Through this case report, we hope to deepen understanding of rare metastasis of esophageal squamous cell carcinoma and actively promote local radiotherapy plus chemotherapy and immunotherapy to improve survival.
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