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Mobile Phone Use, Genetic Susceptibility and New-Onset Chronic Kidney Diseases

Yuanyuan Zhang1,2,3,4, Yanjun Zhang1,2,3,4, Ziliang Ye1,2,3,4

  • 1Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

International Journal of Public Health
|March 6, 2023
PubMed

Insights

Mobile phone use is linked to a higher risk of developing chronic kidney disease (CKD). Increased call time, particularly over 30 minutes weekly, significantly elevates this risk, especially for those with genetic predispositions.

Area of Science:

  • Nephrology
  • Epidemiology
  • Environmental Health

Background:

  • Chronic kidney disease (CKD) is a significant global health concern.
  • Understanding modifiable risk factors for CKD is crucial for prevention.
  • The impact of mobile phone usage patterns on CKD incidence requires investigation.

Purpose of the Study:

  • To investigate the association between mobile phone use and new-onset CKD.
  • To explore how specific mobile phone usage characteristics influence CKD risk.
  • To identify high-risk groups for CKD based on mobile phone habits and genetic predisposition.

Main Methods:

  • A large cohort study utilizing UK Biobank data from 408,743 participants without prior CKD.
  • Prospective follow-up for a median of 12.1 years to ascertain new-onset CKD.
  • Statistical analyses including hazard ratios (HR) and propensity score matching to assess associations.

Main Results:

  • Mobile phone users exhibited a significantly higher risk of new-onset CKD compared to non-users (HR=1.07).
  • Weekly call times of 30 minutes or more were associated with a significantly increased CKD risk (HR=1.12).
  • The highest CKD risk was observed in individuals with both high genetic risk and longer mobile phone usage.

Conclusions:

  • Mobile phone use is significantly associated with an increased risk of developing new-onset CKD.
  • Longer weekly call times on mobile phones are a key factor contributing to this elevated risk.
  • Further research is warranted to elucidate the mechanisms underlying this association.

Keywords:
UK biobankchronic kidney diseasescohort studymaking or receiving callsmobile phones uses

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