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Updated: Aug 8, 2025
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Human parechovirus meningoencephalitis
Pokhraj P Suthar1, Kathryn Hughes1, Geetanjalee Kadam1
1Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.
Abstract:
Human parechovirus-3 (HPeV-3) infection is one of the differential diagnoses of neonatal meningoencephalitis. A 13-day-old full-term female neonate presented with a seizure. Brain MRI showed classic imaging findings of the meningoencephalitis which was confirmed on cerebrospinal fluid analysis.
Contribution:
The HPeV-3 is an emerging pathogen for neonatal meningoencephalitis. The case in this study is unique with classic imaging findings, which are not routinely encountered in day-to-day practice. This case raises reader awareness.
Insights
Human parechovirus-3 (HPeV-3) infection can cause neonatal meningoencephalitis. This case highlights classic brain MRI findings in an infant, aiding in early diagnosis of this emerging pathogen.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Neonatal meningoencephalitis requires prompt diagnosis and management.
- Human parechovirus-3 (HPeV-3) is an emerging cause of central nervous system infections in neonates.
- Characteristic neuroimaging findings can aid in early HPeV-3 diagnosis.
