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Related Concept Videos

Phylogenetic Trees03:21

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Large Scale Energy Efficient Sensor Network Routing Using a Quantum Processor Unit
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Data on the solution and processing time reached when constructing a phylogenetic tree using a quantum-inspired

Wataru Onodera1, Nobuyuki Hara2, Shiho Aoki1

  • 1Faculty of Science and Engineering, Waseda University, TWIns, 2-2 Wakamatsu, Shinjuku, Tokyo 162-8480, Japan.

Data in Brief
|March 6, 2023
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Summary

Constructing phylogenetic trees is computationally intensive. This study introduces a novel method using a quantum-inspired computer to rapidly generate optimal phylogenetic trees by solving graph-cut problems, offering a faster alternative for evolutionary analysis.

Keywords:
Distance-matrix methodGraph cutPhylogenetic reconstructionQuantum-inspired computing

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Area of Science:

  • Computational Biology
  • Phylogenetics
  • Quantum Computing Applications

Background:

  • Phylogenetic trees are crucial for understanding species and molecular evolution.
  • Traditional phylogenetic tree construction methods face combinatorial explosion challenges, limiting scalability.
  • Brute-force approaches to determine optimal trees are computationally infeasible for large datasets.

Purpose of the Study:

  • To develop a high-speed method for constructing optimal phylogenetic trees.
  • To leverage quantum-inspired computing for solving complex combinatorial optimization problems in phylogenetics.
  • To compare the performance of the novel method against existing phylogenetic tree reconstruction techniques.

Main Methods:

  • Developed a phylogenetic tree construction method utilizing the Fujitsu Digital Annealer, a quantum-inspired computer.
  • The method involves partitioning sequence sets, framed as a graph-cut problem.
  • Optimality was assessed using the normalized cut value and compared with existing methods on simulated and real data.

Main Results:

  • The quantum-inspired approach successfully generated phylogenetic trees by efficiently solving graph-cut problems.
  • Performance was evaluated on diverse simulated datasets (32-3200 sequences) with varying evolutionary parameters.
  • The method demonstrated a viable alternative for constructing phylogenetic trees, addressing computational limitations.

Conclusions:

  • A novel, high-speed phylogenetic tree construction method using quantum-inspired computing has been successfully developed.
  • This approach offers a significant advancement over traditional methods, particularly for large-scale evolutionary analyses.
  • The study provides a valuable dataset and methodology for future research in phylogenetic tree reconstruction.