Related Experiment Video
Updated: Aug 8, 2025
07:41
Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse
Published on: April 17, 2019
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Pelvic Organ Prolapse in Ehlers-Danlos Syndrome
Azadeh Nazemi1, Katherine Shapiro1, Shavy Nagpal1
1Department of Urology, New York University Grossman School of Medicine New York, NY, USA.
Case Reports in Urology
|March 6, 2023
Summary
Ehlers-Danlos syndrome (EDS) complicates pelvic floor disorder treatment. This study highlights a multidisciplinary approach for managing pelvic organ prolapse in EDS patients, emphasizing tailored care for these complex cases.
Area of Science:
- Connective tissue disorders
- Gynecology and obstetrics
- Pelvic floor disorders
Background:
- Ehlers-Danlos syndrome (EDS) is a group of inherited disorders affecting collagen synthesis.
- It predisposes individuals to various complications, including gynecologic and obstetric issues.
- Pelvic floor disorders (PFDs) are common in female EDS patients, requiring specialized management.
Observation:
- Three unique cases of pelvic organ prolapse (POP) in patients with Ehlers-Danlos syndrome are presented.
- These cases illustrate the challenges in managing PFDs in the context of EDS.
- The complexity of EDS necessitates careful consideration for treatment strategies.
Findings:
- Successful management of POP in EDS requires a comprehensive, multidisciplinary approach.
- Collaboration between urogynecology, rheumatology, physiatry, gastroenterology, and anesthesiology is crucial.
- Tailored treatment plans are essential due to the underlying connective tissue abnormalities.
Implications:
- This approach can improve outcomes for EDS patients with PFDs.
- It underscores the importance of integrated care models for rare connective tissue diseases.
- Further research into EDS-specific PFD treatments is warranted.
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