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Updated: Aug 8, 2025
Neonatal Pial Surface Electroporation
Published on: May 7, 2014
Neonatal extravasation injuries: neonatal unit reflection and literature review
Suhair Abd Elrahim Othman1, Rawan E Ali2
1Consultant Paediatrician and Neonatologist, Professor of Paediatrics, Red Sea University, Port Sudan, Sudan.
Insights
Neonatal extravasation injuries are common in preterm infants, with over half affected. Significant injuries occurred in 11.2%, highlighting the need for preventative measures in neonatal units.
Area of Science:
- Neonatal care
- Pediatric surgery
- Clinical research
Background:
- Extravasation injury involves tissue damage from infiltrated drugs or infusates.
- Preterm infants face heightened susceptibility due to physiological immaturity.
Purpose of the Study:
- To determine the prevalence of extravasation injury in a neonatal unit.
- To raise awareness of this significant issue in neonatal care settings.
Main Methods:
- Observational, longitudinal, hospital-based study.
- Inclusion of all preterm infants admitted to Sea Port Hospital Neonatal Unit (February 2012-February 2019).
- Exclusion of infants with congenital or transient skin diseases.
Main Results:
- Out of 434 preterm infants, 249 (57.4%) experienced extravasation.
- A significant 11.2% of affected infants sustained severe injuries.
Conclusions:
- Neonatal extravasation injuries are prevalent and concerning in neonatal units.
- Implementation of screening, prevention, and treatment strategies is crucial.
Abstract:
Extravasation injury is tissue infiltration and injury related to drugs or infusates. Preterm infants are most susceptible due to many factors related to their prematurity. Our aim was to report on the prevalence of extravasation injury in our neonatal unit to attract attention to the existence of this problem in the neonatal units. This is an observational, longitudinal, hospital-based study, conducted in the period from February 2012 to February 2019. All preterm infants admitted to Sea Port Hospital Neonatal Unit, Port Sudan City, Sudan, were included. Infants with any other congenital or transient skin diseases were ruled out. From 434 preterm infants admitted, 249 (57.4%) infants were affected and 28 (11.2%) of them were injured significantly. We concluded that neonatal extravasation injuries (including severe forms) are significantly observed in our neonatal unit, and measures to screen for, avoid, and treat this morbidity, should be implemented.
