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Male Breast Imaging Uncovers Lymphoma
Luma Abunimer1, Sophia R O'Brien2, Nabil Calisi3
1Virginia Tech Carilion School of Medicine, Roanoke, VA, USA.
Journal of Radiology Case Reports
|March 6, 2023
Summary
A 36-year-old man was diagnosed with Classic Hodgkin lymphoma via breast imaging, highlighting its role in diagnosing rare male lymphoma cases. This case underscores the importance of breast imaging in diverse patient populations for detecting lymphoproliferative disorders.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- A 36-year-old male presented with a four-month history of a palpable right axillary mass.
- No family history of breast cancer was reported.
- The patient underwent breast imaging for diagnostic evaluation.
Observation:
- Breast imaging, including mammography, targeted ultrasound, and MRI, was performed.
- MRI suggested a lymphoproliferative disorder.
- Excisional biopsy of the axillary tissue revealed Classic Hodgkin lymphoma, nodular sclerosis type.
Findings:
- The excisional biopsy specimen measured 15.0 × 5.5 × 2.0 cm and contained multiple lymph nodes.
- Staging [18F]-FDG PET/CT indicated an early stage of the disease.
Implications:
- This case highlights the unusual presentation of lymphoma in a male patient.
- It emphasizes the critical role of breast imaging in the diagnostic work-up of lymphoproliferative disorders across diverse populations.
- The findings underscore the importance of considering lymphoma in the differential diagnosis of axillary masses, regardless of patient demographics.

