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Assessment of Cardiac Morphological and Functional Changes in Mouse Model of Transverse Aortic Constriction by Echocardiographic Imaging
Published on: June 21, 2016
Cardiac imaging in rheumatic heart disease and future developments
Samuel Seitler1, Mohamed Zuhair1, Aamir Shamsi1
1Royal Free Hampstead NHS Trust, Royal Free London NHS Foundation Trust, Pond St, London NW3 2QG, UK.
Insights
Rheumatic heart disease (RHD) diagnosis relies heavily on echocardiography, but current criteria face challenges. New tools like handheld echocardiography may improve RHD screening, especially in underserved regions.
Area of Science:
- Cardiology
- Medical Imaging
- Public Health
Background:
- Rheumatic heart disease (RHD) is a leading cause of valvular heart disease globally, disproportionately affecting low- and middle-income countries.
- Current diagnostic imaging for RHD, while evolving, faces challenges with complexity and reproducibility.
- There's a critical need for practical and sensitive screening tools for RHD.
Purpose of the Study:
- To review current and emerging cardiac imaging techniques for Rheumatic Heart Disease (RHD).
- To discuss the limitations of existing RHD diagnostic criteria and the need for improved methods.
- To explore the potential of novel imaging technologies, such as handheld echocardiography, in RHD management.
Main Methods:
- Review of current literature on cardiac imaging modalities in RHD diagnosis and management.
- Analysis of established and developing criteria for RHD diagnosis.
- Examination of advancements in echocardiography, including 2D and handheld devices.
Main Results:
- Two-dimensional transthoracic echocardiography is the primary imaging modality for RHD.
- Existing diagnostic criteria (e.g., World Heart Foundation 2012) have limitations in simplicity and reproducibility.
- Handheld echocardiography shows promise for RHD screening in resource-limited settings but requires further validation.
Conclusions:
- Significant challenges persist in the imaging and screening of RHD, necessitating further research and development.
- Advancements in cardiac imaging, particularly portable solutions, could transform RHD care in underserved populations.
- A balance between accuracy and practicality is crucial for effective RHD diagnostic and screening tools.
Abstract:
Rheumatic heart disease (RHD) is the most common cause of valvular heart disease worldwide, affecting millions, especially in low- and middle-income countries. Multiple imaging modalities such as cardiac CT, cardiac MRI, and three-dimensional echocardiography may be utilized in diagnosing, screening, and managing RHD. However, two-dimensional transthoracic echocardiography remains the cornerstone of imaging in RHD. Criteria developed by the World Heart Foundation in 2012 sought to unify the diagnostic imaging criteria for RHD, but concerns remain regarding their complexity and reproducibility. In the intervening years, further measures have been developed to find a balance between simplicity and accuracy. Nonetheless, there remain significant unresolved problems within imaging in RHD, including the development of a practical and sensitive screening tool to identify patients with RHD. The emergence of handheld echocardiography has the potential to revolutionize RHD management in resource-poor settings, but its role as a screening or diagnostic tool is yet to be fully established. The dramatic evolution of imaging modalities over the last few decades has not addressed RHD compared to other forms of structural heart disease. In this review, we examine the current and latest developments concerning cardiac imaging and RHD.
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