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Use of a Hanging-weight System for Isolated Renal Artery Occlusion
07:54

Use of a Hanging-weight System for Isolated Renal Artery Occlusion

Published on: July 19, 2011

Haemodialysis without heparin

H F Woods, M J Weston, S Bunting

    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
    |January 1, 1978
    PubMed

    Despite the use of heparin, activation of platelets on the artificial surface of dialyser membranes results in thrombus formation, microembolisation and thrombocytopenia. To assess the effects on these events of prostacyclin, three groups of healthy greyhounds were dialysed with heparin, heparin plus prostacyclin or prostacyclin alone. The use of prostacyclin, either alone or with heparin, abolished microembolisation from the dialyser and prevented thrombbocytopenia. With prostacyclin dialysis could be carried out without heparin and there was no clotting of blood within the extracorporeal circuit nor any change in tests of haemostasis.

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