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[The interoperability of IIEF-5 with EPIC-26 : Sexual function after radical prostatectomy].

F Fischer1, C Kowalski2, J Simon1

  • 1Medizinische Klinik mit Schwerpunkt Psychosomatik, Charité - Universitätsmedizin Berlin corporate member of Freie Universität Berlin Humboldt-Universität zu Berlin und Berlin Institute of Health, Berlin, Deutschland.

Urologie (Heidelberg, Germany)
|March 6, 2023
PubMed
Summary

The International Index of Erectile Function-5 (IIEF-5) and Expanded Prostate Cancer Index Composite-26 (EPIC-26) sexuality domain measure similar constructs in prostate cancer patients. While individual score conversion is uncertain, group-level comparisons are accurate.

Keywords:
CertificationErectile dysfunctionOutcomeProstate neoplasmSexual intercourse

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Area of Science:

  • Urology
  • Oncology
  • Health Outcomes Research

Context:

  • The International Index of Erectile Function-5 (IIEF-5) was historically used for erectile function assessment in prostate cancer patients.
  • The Expanded Prostate Cancer Index Composite-26 (EPIC-26) sexuality domain is increasingly adopted in Germany for similar assessments.
  • A practical comparison between IIEF-5 and EPIC-26 sexuality domain is needed for evaluating historical patient data.

Purpose:

  • To compare the IIEF-5 and the EPIC-26 sexuality domain for prostate cancer patients in Germany.
  • To establish a method for converting IIEF-5 scores to EPIC-26 sexuality domain scores for historical data evaluation.

Summary:

  • A study analyzed 2123 prostate cancer patients who completed both IIEF-5 and EPIC-26 questionnaires.
  • Linear regression was used to convert IIEF-5 sum scores to EPIC-26 sexuality domain scores.
  • A high correlation (0.74) was found between IIEF-5 and EPIC-26 sexuality domain scores, indicating content convergence.

Impact:

  • Individual score conversion between IIEF-5 and EPIC-26 is associated with significant uncertainty due to wide prediction intervals.
  • Accurate prediction of EPIC-26 sexuality scores at the group level is achievable.
  • This facilitates the comparison of erectile function across patient cohorts assessed with different instruments.