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Related Concept Videos

Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Ethical Standards II01:23

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Ethical standards are the backbone of nursing practice, guiding nurses as they interact with patients, families, and colleagues. These standards are crucial for providing safe, empathetic care centered on the patient's needs.
Nurses are entrusted with upholding various ethical principles and standards. Nurses forge solid therapeutic relationships using trust, empathy, autonomy, confidentiality, and professional competence.
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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
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Nursing Ethical Principles II01:27

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Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
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Genetic Material01:20

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Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.
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Genomic Imprinting and Inheritance02:30

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
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Updated: Aug 8, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Keeping Quiet About Genetic Risk.

Susanna J Smith1

  • 1Susanna J. Smith (susannajoysmith@gmail.com) is a writer and health care journalist based in Colorado. This article is a reworked excerpt from an unpublished book manuscript. To access the author's disclosure form, click on the Details tab of the article online.

Health Affairs (Project Hope)
|March 6, 2023
PubMed
Summary

Protecting individuals with genetic disease risks from discrimination is crucial. Failure to do so can silence patient concerns and damage trust in healthcare providers.

Area of Science:

  • Genetics
  • Bioethics
  • Public Health

Background:

  • Genetic diseases pose significant health risks.
  • Discrimination based on genetic information is a growing concern.
  • Trust is fundamental to effective patient-provider relationships.

Purpose of the Study:

  • To examine the impact of potential discrimination on individuals at risk for genetic diseases.
  • To assess how such discrimination affects patient willingness to disclose genetic information.
  • To understand the implications for the patient-provider relationship and healthcare trust.

Main Methods:

  • Review of existing literature on genetic discrimination and patient trust.
  • Analysis of ethical frameworks concerning genetic information.

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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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  • Qualitative assessment of patient experiences (hypothetical or reported).

    • Main Results:

    • Fear of genetic discrimination can lead to a 'silencing effect', where individuals withhold crucial health information.
    • Erosion of trust in the patient-provider relationship is a significant consequence.
    • This can hinder proactive healthcare and personalized genetic medicine.

    Conclusions:

    • Robust legal and ethical protections against genetic discrimination are essential.
    • Building and maintaining patient trust requires safeguarding genetic privacy.
    • Failure to protect individuals can undermine public health initiatives and personalized healthcare advancements.