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Novel approaches to managing gestational trophoblastic tumors in the age of immunotherapy

Lindsay Hennah1, Michael Seckl2, Ehsan Ghorani2

  • 1Department of Medical Oncology, Imperial College Healthcare NHS Trust, London, UK.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
|March 6, 2023
PubMed

The discovery that anti-programmed death-1 antibody (anti-PD-1) immunotherapy can cure patients with multidrug-resistant gestational trophoblastic neoplasia provides a new powerful and low toxicity treatment. This heralds an era within which the majority of patients, including those with previously difficult to treat disease, can expect to achieve long-term remission. This development should prompt a rethink of how patients with this rare disease are managed, focusing on maximizing cure rate with minimal exposure to toxic chemotherapy.

Keywords:
Gestational Trophoblastic Disease

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