International consensus statement on allergy and rhinology: Allergic rhinitis - 2023

Area of Science:

• Otolaryngology
• Allergy and Immunology

Background:

• The 2018 International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR-Allergic Rhinitis 2018) has been significantly updated.
• Substantial expansion in literature necessitated a comprehensive review of allergic rhinitis (AR).

Purpose of the Study:

• To present an updated, evidence-based evaluation of 144 topics related to allergic rhinitis (AR).
• To incorporate new findings and revise existing knowledge since the 2018 consensus statement.

Main Methods:

• Utilized the established evidence-based review with recommendation (EBRR) methodology.
• Conducted stepwise iterative peer review and consensus for each of the 144 topics.
• Collated aggregate grades of evidence and developed recommendation summaries.

Main Results:

• The 2023 update covers 10 major content areas and 144 individual topics on AR.
• Aggregate grades of evidence are presented for a substantial proportion of topics.
• Recommendation summaries consider evidence, benefit, harm, and cost for interventions.

Conclusions:

• ICAR-Allergic Rhinitis 2023 offers a comprehensive assessment of current AR knowledge.
• The updated evidence base informs contemporary recommendations for AR patient evaluation and treatment.