Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Blood pressure and cognitive performance. The Framingham Study.

M E Farmer¹, L R White, R D Abbott

¹Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD 20892.

American Journal of Epidemiology

|December 1, 1987

Summary

This study found no significant link between blood pressure levels and cognitive performance in older adults. Blood pressure and hypertension treatment did not impact cognitive function in the Framingham Heart Study participants.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Author Correction: Computed tomographic perfusion imaging for the prediction of response transarterial radioembolization with Yttrium‑90 glass microspheres of hepatocellular carcinoma.

European review for medical and pharmacological sciences·2021

Same author

Feasibility and safety of cangrelor in patients with suboptimal P2Y<sub>12</sub> inhibition undergoing percutaneous coronary intervention: rationale of the Dutch Cangrelor Registry.

BMC cardiovascular disorders·2021

Same author

Computed tomographic perfusion imaging for the prediction of response transarterial radioembolization with Yttrium‑90 glass microspheres of hepatocellular carcinoma.

European review for medical and pharmacological sciences·2021

Same author

Everolimus-eluting bioresorbable vascular scaffold in daily clinical practice: A single-centre experience.

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·2017

Same author

Perceptions of classroom environment and their relationship to children's mood, achievement, popularity and adjustment.

The journal of primary prevention·2013

Same author

Rocks, soils, and water quality. Relationships and implications for effects of acid precipitation on surface water in the Northeastern United States.

Environmental science & technology·2012

Area of Science:

Neuroscience
Cardiology
Gerontology

Background:

Elevated blood pressure is a known risk factor for cardiovascular disease.
The relationship between blood pressure and cognitive function in aging populations requires further investigation.
Previous research has yielded conflicting results regarding blood pressure's impact on cognition.

Purpose of the Study:

To examine the association between systolic and diastolic blood pressure and cognitive performance in older adults.
To determine if antihypertensive medication use influences the relationship between blood pressure and cognition.
To investigate cognitive function in relation to blood pressure in the Framingham Heart Study cohort.

Main Methods:

Neuropsychological testing of 2,123 participants aged 55-89.

Related Experiment Videos

Analysis of cognitive performance against blood pressure measurements, controlling for covariates.

Exclusion of participants with a history of stroke from the primary analysis.

Main Results:

No significant association was found between blood pressure (systolic or diastolic) and cognitive performance in 2,032 participants.
Antihypertensive medication use did not mediate the relationship between blood pressure and cognitive function.
Excluding individuals on medication confirmed blood pressure's unrelatedness to cognitive performance.

Conclusions:

Blood pressure and its treatment were not significantly associated with cognitive performance in this cohort.
Findings suggest no consistent link between blood pressure and cognitive function in older adults, contrary to some prior studies.
Further research may be needed to explore other factors influencing cognitive health in aging individuals.