Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of sonication on staphylococcal and gram-negative biofilms relevant to prosthetic joint infections: an in vitro study.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]·2026
Same author

Intravitreal dexamethasone sodium phosphate challenge to predict implant response in refractory diabetic macular edema: a pilot study.

Arquivos brasileiros de oftalmologia·2026
Same author

Association between axial length and perfluoropropane gas duration after pars plana vitrectomy with fixed-volume pure gas injection.

Arquivos brasileiros de oftalmologia·2025
Same author

Esmolol as an Adjunct in Multimodal Anesthesia: A Systematic Review and Meta-Analysis of Its Opioid-Sparing and Analgesic Effects.

Anesthesia and analgesia·2025
Same author

Dose adjustment of intravitreal medications and gases according to axial length and vitreous cavity volume.

Arquivos brasileiros de oftalmologia·2025
Same author

Intravitreal aflibercept alone versus combination with dexamethasone phosphate for diabetic macular edema: A randomized phase-2 clinical trial.

Arquivos brasileiros de oftalmologia·2025

Related Experiment Video

Updated: Jun 11, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.6K

Comparison of Retinal Structure Using Optical Coherence Tomography Angiography between Persons with and without HIV

Luana Nogueira Brandão1,2,3, Rodrigo Pessoa Cavalcanti Lira3, Tiago Eugênio Faria E Arantes4

  • 1Medical School, Federal University of Alagoas, Arapiraca, Brazil.

Ocular Immunology and Inflammation
|March 7, 2023
PubMed
Summary

Optical coherence tomography angiography (OCTA) detects early retinal changes in individuals with HIV, showing reduced blood flow and thinning before clinical signs of retinopathy appear.

Keywords:
HIVmicroangiopathicoptic diskoptical coherence tomography angiographyretina

More Related Videos

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

1.9K
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

251

Related Experiment Videos

Last Updated: Jun 11, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
07:23

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

7.6K
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

1.9K
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

251

Area of Science:

  • Ophthalmology
  • Vascular Biology
  • Infectious Diseases

Background:

  • HIV-associated retinopathy poses a mortality risk.
  • Optical coherence tomography angiography (OCTA) visualizes microvascular changes.
  • Early detection of retinal alterations in HIV is crucial.

Purpose of the Study:

  • To investigate microvascular and structural retinal changes in individuals with HIV using OCTA.
  • To compare retinal vascularization and nerve fiber layer thickness between HIV-positive and healthy individuals.
  • To determine if OCTA can identify subclinical retinopathy in HIV.

Main Methods:

  • A comparative study involving 25 individuals with HIV and 25 healthy controls.
  • OCTA was employed to assess vascularization in retinal plexuses, choriocapillary, and optic disk.
  • Measurements included vessel flow density (VFD), retinal nerve fiber layer (RNFL) thickness, and optic disk rim area.

Main Results:

  • The HIV group exhibited significantly lower VFD in the superficial retinal plexus compared to controls.
  • No significant differences in deep plexus VFD or optic disk/peripapillary VFD were found.
  • The HIV group presented with thinner RNFL and a smaller optic disk rim area.

Conclusions:

  • HIV infection is associated with reduced VFD in the superficial retinal plexus.
  • Subclinical retinal nerve fiber layer thinning and optic disk rim area reduction occur in HIV.
  • OCTA can detect early retinal microvascular and structural changes in HIV patients, preceding funduscopic evidence of retinopathy.