Jove
Visualize
Contact Us

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

512
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
512
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

330
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
330
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

16
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
16
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

12
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
12

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predicting Intensive Care Readmission Among Hospitalized Children.

medRxiv : the preprint server for health sciences·2026
Same author

Simulation-Based Peer Feedback Module for Pediatric Rapid Response Team Handoffs.

MedEdPORTAL : the journal of teaching and learning resources·2025
Same author

Ethics in the Emergency Department: Withholding or Terminating Resuscitation.

Pediatric emergency care·2025
Same author

Explaining alerts from a pediatric risk prediction model using clinical text.

Journal of the American Medical Informatics Association : JAMIA·2025
Same author

Machine Learning for Predicting Critical Events Among Hospitalized Children.

JAMA network open·2025
Same author

Machine Learning-Based Pediatric Early Warning Score: Patient Outcomes in a Pre- Versus Post-Implementation Study, 2019-2023.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Aug 7, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

2.5K

Multisystem Inflammatory Syndrome in Children.

Chidimma Acholonu, Erin Cohen, Sarah Y Afzal

    Pediatric Annals
    |March 7, 2023
    PubMed
    Summary
    This summary is machine-generated.

    Multisystem inflammatory disease in children (MIS-C) is a hyperinflammatory response to SARS-CoV-2 infection, presenting with fever and organ dysfunction weeks after COVID-19. Diagnosis involves excluding other causes and assessing cardiac function.

    More Related Videos

    The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
    12:04

    The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

    Published on: November 1, 2015

    17.8K
    Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
    12:18

    Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

    Published on: February 9, 2011

    23.0K

    Related Experiment Videos

    Last Updated: Aug 7, 2025

    Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
    08:44

    Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

    Published on: September 7, 2022

    2.5K
    The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
    12:04

    The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

    Published on: November 1, 2015

    17.8K
    Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
    12:18

    Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA

    Published on: February 9, 2011

    23.0K

    Area of Science:

    • Pediatric infectious diseases
    • Immunology
    • Cardiology

    Background:

    • Multisystem inflammatory disease in children (MIS-C) is a rare but serious condition following SARS-CoV-2 infection.
    • It is characterized by a hyperinflammatory state affecting multiple organ systems.
    • MIS-C typically occurs 3-6 weeks after an asymptomatic or mild COVID-19 infection.

    Purpose of the Study:

    • To summarize the clinical presentation, diagnostic criteria, and key evaluations for MIS-C.
    • To highlight the importance of early recognition and management of this post-infectious sequela.

    Main Methods:

    • Review of clinical manifestations including fever, organ system dysfunction, and common symptoms like skin/mucosal, GI, and neurological involvement.
    • Diagnostic criteria include vital sign instability, elevated inflammatory and cardiac markers, and confirmed SARS-CoV-2 exposure or infection.
    • Echocardiography is essential for assessing cardiac involvement, such as coronary artery abnormalities and ventricular dysfunction.

    Main Results:

    • MIS-C presents with persistent fever and dysfunction in at least two organ systems.
    • Diagnosis is one of exclusion, requiring differentiation from other infectious and non-infectious conditions.
    • Cardiac dysfunction is a significant concern, necessitating echocardiographic evaluation.

    Conclusions:

    • MIS-C is a distinct post-infectious syndrome requiring prompt diagnosis and management.
    • Multidisciplinary care involving infectious disease specialists, immunologists, and cardiologists is crucial.
    • Early identification and treatment can mitigate severe complications, particularly cardiac sequelae.