A Case of Neonatal Myeloid Sarcoma

Here we describe a cutaneous neonatal myeloid sarcoma (MS) case with a subsequent diagnosis of acute myeloid leukemia (AML) seven days later. Cytogenetic studies were unusual demonstrating a triple copy of KAT6A abnormality and complex 8;14;22 translocation involving the 8p11.2 region. MS may be the initial finding suggesting associated AML; therefore, the diagnosis of cutaneous MS may allow for expeditious evaluation/treatment of such leukemic disorders.