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Minimally Invasive versus Open Ureteral Reimplantation in Children: A Systematic Review and Meta-Analysis
Shaoguang Feng1,2, Zhechen Yu2, Yicheng Yang2
1Department of Pediatric Surgery, Hangzhou Children's Hospital, Hangzhou, China.
Purpose:
We performed a systematic review and meta-analysis to compare the safety and efficacy of minimally invasive surgery (MIS) versus open ureteral reimplantation (OUR) in children.
Methods:
Literature searches were conducted to identify studies that compared MIS (laparoscopic ureteral reimplantation or robot-assisted laparoscopic ureteral replantation) and OUR in children. Parameters such as operative time, blood loss, length of hospital stay, success rate, postoperative urinary tract infection (UTI), urinary retention, postoperative hematuria, wound infection, and overall postoperative complications were pooled and compared by meta-analysis.
Results:
Among the 7,882 pediatric participants in the 14 studies, 852 received MIS, and 7,030 received OUR. When compared with the OUR, the MIS approach resulted in shorter hospital stays (I 2 = 99%, weighted mean difference [WMD] -2.82, 95% confidence interval [CI] -4.22 to -1.41; p < 0.001), less blood loss (I 2 = 100%, WMD -12.65, 95% CI -24.82 to -0.48; p = 0.04), and less wound infection (I 2 = 0%, odds ratio 0.23, 95% CI 0.06-0.78; p = 0.02). However, no significant difference was found in operative time and secondary outcomes such as postoperative UTI, urinary retention, postoperative hematuria, and overall postoperative complications.
Conclusion:
MIS is a safe, feasible, and effective surgical procedure in children when compared with OUR. Compared with OUR, MIS has a shorter hospital stay, less blood loss, and less wound infection. Furthermore, MIS is equivalent to OUR in terms of success rate and secondary outcomes such as postoperative UTI, urinary retention, postoperative hematuria, and overall postoperative complications. We conclude that MIS should be considered an acceptable option for pediatric ureteral reimplantation.
Insights
Minimally invasive surgery (MIS) for pediatric ureteral reimplantation offers shorter hospital stays and less blood loss compared to open surgery. MIS is a safe and effective alternative, demonstrating comparable success rates and complication profiles to open ureteral reimplantation (OUR).
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Surgical Outcomes
Background:
- Ureteral reimplantation is a common procedure for pediatric reflux.
- Minimally invasive surgery (MIS) approaches, including laparoscopic and robot-assisted techniques, are increasingly utilized.
- Comparing MIS with traditional open ureteral reimplantation (OUR) is crucial for optimizing pediatric surgical care.
Purpose of the Study:
- To systematically review and meta-analyze the safety and efficacy of MIS versus OUR in pediatric patients.
- To compare key perioperative and postoperative outcomes between MIS and OUR.
- To determine if MIS is a viable alternative to OUR for pediatric ureteral reimplantation.
Main Methods:
- Systematic literature search for comparative studies of MIS (laparoscopic/robot-assisted) and OUR in children.
- Meta-analysis of pooled data on operative time, blood loss, hospital stay, success rate, and complications (UTI, retention, hematuria, wound infection).
- Statistical comparison of outcomes using weighted mean differences and odds ratios with 95% confidence intervals.
Main Results:
- Analysis of 14 studies involving 7,882 pediatric participants (852 MIS, 7,030 OUR).
- MIS was associated with significantly shorter hospital stays (WMD -2.82 days), less blood loss (WMD -12.65 mL), and reduced wound infection rates (OR 0.23) compared to OUR.
- No significant differences were observed in operative time, success rates, postoperative UTI, urinary retention, hematuria, or overall complications.
Conclusions:
- Minimally invasive surgery (MIS) is a safe, feasible, and effective option for pediatric ureteral reimplantation.
- MIS offers advantages over open ureteral reimplantation (OUR) including shorter hospital stays, reduced blood loss, and fewer wound infections.
- MIS demonstrates equivalent efficacy and safety profiles to OUR regarding success rates and secondary outcomes, supporting its consideration as an acceptable surgical choice.
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