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How I prescribe prolonged intermittent renal replacement therapy
Edward G Clark1, Anitha Vijayan2
1Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Canada. edclark@toh.ca.
Critical Care (London, England)
|March 7, 2023
Summary
Prolonged Intermittent Renal Replacement Therapy (PIRRT) offers a flexible hybrid dialysis approach. This cost-effective method provides safe renal replacement therapy for critically ill patients in the ICU.
Area of Science:
- Nephrology
- Critical Care Medicine
Background:
- Prolonged Intermittent Renal Replacement Therapy (PIRRT) represents a hybrid modality of renal replacement therapy.
- PIRRT bridges the gap between traditional intermittent hemodialysis and continuous renal replacement therapy.
Purpose of the Study:
- To review the application of PIRRT in the intensive care unit (ICU).
- To outline the prescription protocols for PIRRT in critically ill patients.
Main Methods:
- PIRRT can be administered using either intermittent hemodialysis or continuous renal replacement therapy machines.
- Treatment durations typically range from 6-12 hours, provided 4-7 times per week.
- This contrasts with standard intermittent hemodialysis (3-4 hours) and continuous renal replacement therapy (24 hours).
Main Results:
- PIRRT is identified as a cost-effective and flexible RRT option.
- It allows for safe administration of RRT to critically ill patients.
Conclusions:
- PIRRT is a valuable and adaptable RRT modality for ICU settings.
- Understanding PIRRT prescription is crucial for managing critically ill patients requiring renal support.
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