Related Experiment Videos
Genetic distance analysis using DNA polymorphisms in the alpha-globin gene cluster
K M Summers1, P Yenchitsomanus, R M Chapple
1Department of Human Genetics, John Curtin School of Medical Research, Canberra.
Annals of Human Biology
|September 1, 1987
Abstract:
Published frequencies for alleles at the alpha- and zeta-globin gene loci within the alpha-globin gene cluster were used to calculate genetic distances between populations of South East Asia and the Pacific region. When analyses using the alpha-globin alleles, populations are grouped according to the endemicity of malaria while the groupings derived from the embryonic zeta-globin allele frequencies appear to be far less influenced by the incidence of malaria and probably reflect ancestral or chance relationships due to founder effects, migration and small population sizes.