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Published on: July 19, 2024
An Awkward Fit: Antimicrobial Resistance and the Evolution of International Health Politics (1945-2022)
Claas Kirchhelle1, Scott H Podolsky2
1UNIVERSITY COLLEGE DUBLIN, DUBLIN, IRELAND.
Abstract:
Despite being acknowledged as a major global health challenge, growing levels of antimicrobial resistance (AMR) in pathogenic and commensal organisms have proven an awkward fit for international health frameworks. This article surveys the history of attempts to coordinate international responses to AMR alongside the origins and evolution of the current international health regulations (IHR). It argues that AMR, which encompasses a vast range of microbial properties and ecological reservoirs, is an awkward fit for the 'organismal' philosophies that centre on the rapid control of individual pathogens that have characterised international policy-making since the 19th century.
Insights
Antimicrobial resistance (AMR) poses a global health challenge, but current international health frameworks struggle to address it. This is because AMR
Area of Science:
- Global Health Security
- Infectious Disease Epidemiology
- Microbiology
Background:
- Antimicrobial resistance (AMR) is a significant global health threat.
- Existing international health frameworks face challenges in addressing AMR.
- Current approaches often focus on individual pathogens, not the broader ecological scope of AMR.
Purpose of the Study:
- To analyze the historical coordination of international responses to AMR.
- To examine the evolution of International Health Regulations (IHR) in relation to AMR.
- To explain why AMR is a poor fit for traditional 'organismal' public health policies.
Main Methods:
- Historical survey of international AMR response attempts.
- Analysis of the development of International Health Regulations (IHR).
- Conceptual analysis of AMR's ecological complexity versus pathogen-centric policies.
Main Results:
- Past international efforts to coordinate AMR responses have been fragmented.
- The evolution of IHR has not adequately incorporated the complexities of AMR.
- AMR's broad ecological nature conflicts with historical 'organismal' public health paradigms.
Conclusions:
- Current international health frameworks, including IHR, are ill-suited to tackle the multifaceted challenge of AMR.
- A paradigm shift in international health policy is needed to address AMR effectively.
- Future strategies must account for AMR's ecological reservoirs and diverse microbial properties.
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