An Awkward Fit: Antimicrobial Resistance and the Evolution of International Health Politics (1945-2022)

Claas Kirchhelle1, Scott H Podolsky2

  • 1UNIVERSITY COLLEGE DUBLIN, DUBLIN, IRELAND.

Insights

Antimicrobial resistance (AMR) poses a global health challenge, but current international health frameworks struggle to address it. This is because AMR

Area of Science:

  • Global Health Security
  • Infectious Disease Epidemiology
  • Microbiology

Background:

  • Antimicrobial resistance (AMR) is a significant global health threat.
  • Existing international health frameworks face challenges in addressing AMR.
  • Current approaches often focus on individual pathogens, not the broader ecological scope of AMR.

Purpose of the Study:

  • To analyze the historical coordination of international responses to AMR.
  • To examine the evolution of International Health Regulations (IHR) in relation to AMR.
  • To explain why AMR is a poor fit for traditional 'organismal' public health policies.

Main Methods:

  • Historical survey of international AMR response attempts.
  • Analysis of the development of International Health Regulations (IHR).
  • Conceptual analysis of AMR's ecological complexity versus pathogen-centric policies.

Main Results:

  • Past international efforts to coordinate AMR responses have been fragmented.
  • The evolution of IHR has not adequately incorporated the complexities of AMR.
  • AMR's broad ecological nature conflicts with historical 'organismal' public health paradigms.

Conclusions:

  • Current international health frameworks, including IHR, are ill-suited to tackle the multifaceted challenge of AMR.
  • A paradigm shift in international health policy is needed to address AMR effectively.
  • Future strategies must account for AMR's ecological reservoirs and diverse microbial properties.

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