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Updated: Aug 7, 2025

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
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Streptococcus constellatus Brain Abscess in a Middle-Aged Man With an Undiagnosed Patent Foramen Ovale

Susan G Wager1, Nina K Bourdeau1, Joshua D Collins2

  • 1Internal Medicine, Wayne State University School of Medicine, Detroit, USA.

Cureus
|March 9, 2023
PubMed

Insights

A rare brain abscess caused by oral bacteria, Streptococcus constellatus, occurred in a man due to an undiagnosed patent foramen ovale. This case highlights a unique pathway for brain infection spread.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Cardiology

Background:

  • Brain abscess is an uncommon condition often resulting from direct or hematogenous spread of infection.
  • Oral bacteria can cause brain abscesses, particularly when entering the bloodstream and reaching the brain through cardiac defects.
  • Patent foramen ovale (PFO) is a potential, often undiagnosed, route for such infections.
Keywords:
brain abscesscerebral abscesspatent foramen ovalepforing-enhancing lesionsstreptococcus anginusstreptococcus constellatusteetransesophageal echocardiogram

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