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Lens capsule abnormalities in Alport's syndrome
B W Streeten1, M R Robinson, R Wallace
1Department of Ophthalmology, State University of New York Health Science Center, Syracuse 13210.
Archives of Ophthalmology (Chicago, Ill. : 1960)
|December 1, 1987
Summary
Alport syndrome causes fragile anterior lens capsules, leading to lenticonus and cataracts. This fragility stems from defects in type IV collagen, impacting eye health in affected individuals.
Area of Science:
- Ophthalmology
- Genetics
- Pathology
Background:
- Alport syndrome is known for glomerular basement membrane abnormalities.
- Anterior lenticonus is a common ocular complication of Alport syndrome, but its ultrastructure is poorly understood.
- Previous research has linked Alport syndrome to defects in type IV collagen.