Research Progress of Aging-related MicroRNAs
Zhongyu Chen1, Chenxu Li1, Haitao Huang1
1School of Basic Medicine, Dali University, Dali, Yunnan, 671000, China.
Current Stem Cell Research & Therapy
|March 9, 2023
Summary
Cellular senescence, a key aging factor, involves cell cycle arrest. MicroRNAs (miRNAs) regulate aging, offering potential therapeutic targets for age-related diseases.
Area of Science:
- Gerontology
- Molecular Biology
- Genetics
Background:
- Cellular senescence is a state of irreversible cell cycle arrest.
- Accumulated senescent cells contribute to age-related diseases like cancer and neurodegeneration.
- MicroRNAs (miRNAs) are crucial regulators of gene expression involved in the aging process.
Conclusions:
- Understanding miRNA regulation in aging deepens insights into cellular and body aging.
- miRNAs represent a novel avenue for diagnosing and treating age-related diseases.
- Targeting miRNAs offers prospective clinical applications for senile diseases.
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