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Significant Association between Obsessive-Compulsive Disorder and Atopic Dermatitis - a Retrospective
Sofia Åkerlund1, Oliver Seifert2,3, Johan Assarsson4
1Department of Dermatology and Venereology, Höglandssjukhuset Nässjö, Region Jönköping County, Sweden.
Dermatology Practical & Conceptual
|March 9, 2023
Summary
Patients with atopic dermatitis (AD) have double the risk of developing obsessive-compulsive disorder (OCD). This study highlights the need for dermatologists to screen AD patients for OCD for better outcomes.
Area of Science:
- Dermatology
- Psychiatry
- Epidemiology
Background:
- Atopic dermatitis (AD) is a prevalent global skin condition.
- Limited research exists on the association between AD and obsessive-compulsive disorder (OCD).
Purpose of the Study:
- To investigate the spectrum of diseases associated with atopic dermatitis.
- Specifically examine the link between AD and OCD in Jönköping County, Sweden.
Main Methods:
- Retrospective case-control study (2013-2021).
- Utilized electronic medical records for 398,874 individuals.
- Identified AD cases using ICD-10 codes; compared with controls.
- Regression analysis adjusted for age and gender.
Main Results:
- Found a significant association between AD and OCD (adjusted OR 2.0, 95% CI 1.5-2.7, p<0.001).
- Indicates patients with AD are twice as likely to have OCD.
Conclusions:
- AD and OCD may share common gene-environmental risk factors.
- Dermatologists should consider screening AD patients for OCD for early diagnosis and improved management.
- Further research on larger populations is warranted to explore shared mechanisms.
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