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Amyloid Fibrils

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...

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Related Experiment Video

Updated: Aug 7, 2025

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Performing and Processing FNA of Anterior Fat Pad for Amyloid

Published on: October 30, 2010

Dermal Amyloid Deposits: A Possible Misleading Pathologic Finding

Serena Giacalone^1,2, Carlo Alberto Maronese^1,2, Giovanni Genovese^1,2

¹UOC Dermatologia, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Dermatology Practical & Conceptual

|March 9, 2023

Summary

No abstract available in PubMed .

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Related Experiment Videos

Last Updated: Aug 7, 2025

Performing and Processing FNA of Anterior Fat Pad for Amyloid

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Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

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Published on: March 7, 2019

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