Virtual monochromatic images of dual-energy CT as an alternative to single-energy CT: performance comparison using a...

To investigate the performance of virtual monochromatic (VM) images with the same dose and iodine contrast as those for single-energy (SE) images using five dual-energy (DE) scanners with DE techniques: two generations of fast kV switching (FKS), two generations of dual source (DS), and one split filter (SF).

A water-bath phantom with a diameter of 300 mm, which contains one rod-shaped phantom made of a material equivalent to soft-tissue and two rod-shaped phantoms made of diluted iodine (2 and 12 mg/mL), was scanned using both SE (120, 100, and 80 kV) and DE techniques with the same CT dose index in each scanner. The VM energy at which the CT number of the iodine rod is closest to that of each SE tube voltage was determined as the equivalent energy (Eeq). A detectability index (d') was calculated from the noise power spectrum, the task transfer functions, and a task function corresponding to each rod. The percentage of the d' value of the VM image to that of the corresponding SE image was calculated for performance comparison.

The average percentages of d' of FKS1, FKS2, DS1, DS2, and SF were 84.6%, 96.2%, 94.3%, 107%, and 104% for 120 kV-Eeq; 75.9%, 91.2%, 88.2%, 99.2%, and 82.6% for 100 kV-Eeq; 71.6%, 88.9%, 82.6%, 85.2%, and 62.3% for 80 kV-Eeq, respectively.

The performance of VM images was on the whole inferior to that of SE images especially at low equivalent energy levels, depending on the DE techniques and their generations.

• This study evaluated the performance of VM images with the same dose and iodine contrast as those for SE images using five DE scanners. • The performance of VM images varied with the DE techniques and their generations and was mostly inferior at low equivalent energy levels. • The results highlight the importance of distribution of available dose over the two energy levels and spectral separation for the performance improvement of VM images.