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Updated: Aug 7, 2025

Author Spotlight: Advancements and Challenges in Surgical Treatments for Postamputation Pain
Published on: March 8, 2024
Targeted Muscle Reinnervation in the Setting of Traumatic Bilateral Above-Knee Amputations: A Case Report
Isabel Herzog1, Joseph Weisberger1, Ashley Ignatiuk1
1Rutgers New Jersey Medical School, Newark, New Jersey.
Case:
We present the case of a 20-year-old man who was pedestrian struck and sustained bilateral traumatic above-knee amputations. Targeted muscle reinnervation (TMR) was performed with nerve transfers, including tibial nerve to semitendinosus (bilateral), superficial peroneal nerve to biceps femoris (left), deep peroneal nerve to biceps femoris (left), and common peroneal nerve to biceps femoris (right).
Conclusions:
Less than 1 year postoperatively, the patient was ambulating on his myoelectric prosthesis and experienced no Tinel or neuroma-type pain. This case is a testament to the impact TMR, an innovative surgical technique, can have on the quality of life of patients sustaining devastating limb injuries.

