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Treating Nerve Injury after Endodontic Microsurgery Using Laser Photobiomodulation: A Report of 2 Cases.
Austyn C Grissom1, I Andrea Hernandez1, Timothy C Kirkpatrick1
1Department of Endodontics, The University of Texas Health Science Center at Houston School of Dentistry, Houston, Texas.
Journal of Endodontics
|March 9, 2023
Summary
Photobiomodulation (PBM) therapy offers a noninvasive treatment for iatrogenic nerve injuries in dentistry. This low-level laser therapy demonstrated significant improvement in patients with neurosensory alterations after surgery.
Area of Science:
- Dentistry
- Neurology
- Biomedical Engineering
Background:
- Iatrogenic nerve injuries are a risk in dental procedures, impacting patient quality of life.
- Managing these injuries is challenging due to a lack of standardized protocols.
- Spontaneous nerve healing varies significantly among individuals.
Observation:
- Photobiomodulation (PBM) therapy utilizes low-level laser light to stimulate cellular processes.
- PBM enhances mitochondrial ATP production, modulates reactive oxygen species, and releases nitric oxide.
- These effects promote cell repair, vasodilation, reduced inflammation, and accelerated healing.
Findings:
- This case report details two patients with neurosensory alterations post-endodontic microsurgery.
- Both patients experienced significant condition improvement following PBM treatment.
- A 940-nm diode laser was used for PBM therapy in these cases.
Implications:
- PBM therapy presents a viable, noninvasive treatment option for iatrogenic nerve injuries in dentistry.
- This approach may offer a new management strategy for clinicians facing neural complications.
- Further research into PBM for dental nerve repair is warranted.

