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Rapid maxillary expansion in pediatric patients with obstructive sleep apnea: an umbrella review
Denise Fernandes Barbosa1, Laura Fernandes Bana2, Maria Cristina Buta Michel3
1Universidade de Campinas (UNICAMP), Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Campinas, SP, Brazil.
Insights
Rapid Maxillary Expansion (RME) is not recommended for treating Obstructive Sleep Apnea (OSA) in children due to a lack of consistent evidence. Further high-quality studies are needed to explore RME
Area of Science:
- Pediatric Sleep Medicine
- Orthodontics
- Craniofacial Development
Background:
- Obstructive Sleep Apnea (OSA) in children can cause significant craniofacial changes during critical growth periods.
- Mouth breathing during childhood presents clinical challenges and is associated with OSA.
- Rapid Maxillary Expansion (RME) is being investigated as a potential treatment for pediatric OSA.
Approach:
- An umbrella review systematically searched major electronic databases for systematic reviews with meta-analysis.
- Seven studies measuring the Apnea-Hypopnea Index (AHI) via polysomnography were selected from 40 identified studies on RME for pediatric OSA.
- Data were extracted and analyzed to determine the evidence supporting RME for pediatric OSA treatment.
Key Points:
- No consistent evidence supports the long-term efficacy of RME for treating pediatric OSA.
- Significant heterogeneity was observed across studies, attributed to variations in patient age and follow-up duration.
- The current evidence base necessitates methodologically rigorous studies to clarify RME's role in pediatric OSA.
Conclusions:
- Rapid Maxillary Expansion is not currently recommended for treating Obstructive Sleep Apnea in children.
- Improved study designs are crucial for establishing reliable evidence regarding RME's effectiveness.
- Further research is required to identify early indicators of OSA and standardize treatment practices.
Objective:
To compare polysomnographic parameters with others from the literature in order to provide more accurate information about Rapid Maxillary Expansion (RME) for treating Obstructive Sleep Apnea (OSA) in children, through raising the question: Is RME a good option for treating OSA in children? Prevention of mouth breathing during children's growth remains a challenge with significant clinical consequences. In addition, OSA induces anatomofunctional changes during the critical period of craniofacial growth and development.
Methods:
The Medline, PubMed, EMBASE, CINAHL, Web of Science, SciELO and Scopus electronic databases were searched up to February 2021 for systematic reviews with meta-analysis in the English language. Among 40 studies on RME for treating OSA in children, we selected seven in which polysomnographic measurements of the Apnea-Hypopnea Index (AHI) had been made. Data were extracted and examined in order to clarify whether any consistent evidence exists for indicating RME as a treatment for OSA in children.
Results:
We found no consistent evidence favoring RME for long-term treatment of OSA in children. All the studies presented considerable heterogeneity due to variability of age and length of follow-up.
Conclusion:
Through this umbrella review, the need for methodologically better studies on RME is supported. Moreover, it can be considered that RME is not recommended for treating OSA in children. Further studies and more evidence identifying early signs of OSA are necessary in order to achieve consistent healthcare practice.
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